Christina Alves Peixoto Selected Research

Diethylcarbamazine (Hetrazan)

11/2018	A new diethylcarbamazine formulation (NANO-DEC) as a therapeutic tool for hepatic fibrosis.
4/2018	Diethylcarbamazine attenuates the expression of pro-fibrogenic markers and hepatic stellate cells activation in carbon tetrachloride-induced liver fibrosis.
10/2017	Diethylcarbamazine: A potential treatment drug for pulmonary hypertension?
9/2017	Characterization and evaluation of nanoencapsulated diethylcarbamazine in model of acute hepatic inflammation.
2/2017	Diethylcarbamazine attenuates LPS-induced acute lung injury in mice by apoptosis of inflammatory cells.
4/2015	Diethylcarbamazine: possible therapeutic alternative in the treatment of alcoholic liver disease in C57BL/6 mice.
11/2014	Diethylcarbamazine inhibits NF-κB activation in acute lung injury induced by carrageenan in mice.
1/2014	Diethylcarbamazine attenuates the development of carrageenan-induced lung injury in mice.
1/2014	Diethylcarbamazine reduces chronic inflammation and fibrosis in carbon tetrachloride- (CCl₄-) induced liver injury in mice.
8/2012	Effect of diethylcarbamazine on chronic hepatic inflammation induced by alcohol in C57BL/6 mice.

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Christina Alves Peixoto Research Topics

Disease

21	Inflammation (Inflammations) 01/2022 - 08/2012
12	Neuroinflammatory Diseases 01/2022 - 11/2012
6	Type 2 Diabetes Mellitus (MODY) 12/2021 - 01/2015
5	Demyelinating Diseases (Demyelinating Disease) 01/2022 - 11/2012
5	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2020 - 11/2012
5	Pulmonary Hypertension 10/2017 - 08/2009
4	Neoplasms (Cancer) 01/2021 - 01/2015
4	Body Weight (Weight, Body) 01/2019 - 01/2014
4	Filarial Elephantiasis (Lymphatic Filariasis) 02/2017 - 11/2006
3	Gliosis 08/2020 - 01/2016
3	Pneumonia (Pneumonitis) 04/2018 - 01/2014
3	Atherosclerosis 01/2018 - 01/2012
2	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2015
2	Metabolic Diseases (Metabolic Disease) 12/2021 - 01/2020
2	Alzheimer Disease (Alzheimer's Disease) 09/2021 - 01/2015
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2021 - 08/2020
2	Cognitive Dysfunction 01/2021 - 01/2020
2	Multiple Sclerosis 08/2020 - 01/2015
2	Obesity 01/2020 - 01/2018
2	Fibrosis (Cirrhosis) 11/2018 - 01/2014
2	Liver Cirrhosis (Hepatic Cirrhosis) 11/2018 - 04/2018
2	Non-alcoholic Fatty Liver Disease 01/2018 - 01/2015
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 10/2015
2	Acute Lung Injury 02/2017 - 11/2014
2	Liver Diseases (Liver Disease) 04/2015 - 04/2010
2	Erectile Dysfunction 12/2014 - 12/2009
2	Pleurisy (Pleuritis) 11/2014 - 01/2014
1	Dementia (Dementias) 09/2021
1	Amyloid Plaque 09/2021
1	Leukemia 01/2021
1	Colorectal Neoplasms (Colorectal Cancer) 01/2021
1	Carcinoma (Carcinomatosis) 01/2021
1	Bipolar Disorder (Manic Depressive Psychosis) 01/2021
1	Mania (Manias) 01/2021
1	Hyperammonemia 02/2020
1	Arthritis (Polyarthritis) 01/2020
1	Dysbiosis 01/2020
1	Depressive Disorder (Melancholia) 01/2020
1	Peripheral Nervous System Diseases (PNS Diseases) 09/2019
1	Hyperglycemia 09/2019
1	Atrophy 09/2019
1	Hepatic Encephalopathy 01/2019
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2019
1	Ulcerative Colitis 06/2018
1	Crohn Disease (Crohn's Disease) 06/2018
1	Infertility (Sterility) 05/2018

Drug/Important Bio-Agent (IBA)

12	Diethylcarbamazine (Hetrazan)FDA Link 11/2018 - 11/2006
11	Sildenafil Citrate (Viagra)FDA Link 01/2021 - 08/2009
8	Pharmaceutical PreparationsIBA 09/2021 - 08/2012
6	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2016 - 08/2009
5	CytokinesIBA 08/2020 - 11/2012
4	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 01/2016
4	Neuroprotective AgentsIBA 01/2021 - 01/2013
4	CuprizoneIBA 01/2016 - 11/2012
3	Phosphodiesterase 5 InhibitorsIBA 01/2021 - 08/2009
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2020 - 01/2015
3	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 09/2019 - 07/2014
3	Carbon Tetrachloride (Tetrachloromethane)IBA 11/2018 - 01/2014
3	CollagenIBA 11/2018 - 01/2015
2	Insulin (Novolin)FDA Link 09/2021 - 01/2015
2	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 02/2020 - 01/2015
2	Interleukin-10 (Interleukin 10)IBA 10/2019 - 06/2018
2	InterleukinsIBA 09/2019 - 04/2015
2	NF-kappa B (NF-kB)IBA 01/2019 - 01/2016
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 01/2015
2	Proteins (Proteins, Gene)FDA Link 06/2018 - 01/2015
2	SolutionsIBA 05/2018 - 10/2017
2	LipidsIBA 01/2018 - 04/2010
2	LipopolysaccharidesIBA 11/2016 - 01/2016
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 04/2015 - 07/2014
2	CarrageenanIBA 11/2014 - 01/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2012 - 04/2010
1	Fluoxetine (Prozac)FDA LinkGeneric 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 12/2021
1	Hypoglycemic Agents (Hypoglycemics)IBA 09/2021
1	BiguanidesIBA 09/2021
1	NigericinIBA 01/2021
1	Cytotoxins (Cytolysins)IBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2021
1	Doxycycline (Periostat)FDA LinkGeneric 01/2021
1	LithiumIBA 01/2021
1	Dextroamphetamine (Dexedrine)FDA LinkGeneric 01/2021
1	Guanosine Monophosphate (5' Guanylic Acid)IBA 02/2020
1	PrebioticsIBA 01/2020
1	CarbohydratesIBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 10/2019
1	AntioxidantsIBA 01/2019
1	Glutamate Receptors (Glutamate Receptor)IBA 01/2019
1	SynaptophysinIBA 01/2019
1	Tadalafil (Cialis)FDA Link 01/2019
1	Thioacetamide (Thioacetamid)IBA 01/2019
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019
1	Messenger RNA (mRNA)IBA 06/2018
1	HLA-G Antigens (HLA G)IBA 06/2018
1	gluconic acid (gluconate)FDA LinkGeneric 05/2018

Therapy/Procedure

3	Therapeutics 01/2022 - 12/2014
3	Injections 05/2018 - 01/2014
3	Oral Administration 04/2015 - 11/2012
1	Intraperitoneal Injections 01/2019